Platelet-rich plasma (PRP) therapy is a new therapeutic approach that has gained popularity in various medical fields, including orthopedics, aesthetics, and sexual health, due to its potential benefits. These include:
Orthopedic Benefits

- Tissue Repair
PRP contains growth factors and other bioactive substances that promote tissue repair and regeneration. In orthopedics, PRP injections are commonly used to treat injuries such as tendonitis, ligament sprains, muscle strains, and osteoarthritis. - Pain Reduction
PRP injections may help reduce pain associated with orthopedic conditions by promoting healing and reducing inflammation. - Accelerated Healing
PRP therapy may accelerate the healing process, allowing patients to return to their normal activities more quickly after injury or surgery.
Aesthetic Benefits

- Skin Rejuvenation
PRP is often used in cosmetic procedures to improve skin texture, tone, and elasticity. It can help reduce the appearance of wrinkles, fine lines, and scars. - Hair Restoration
PRP injections can stimulate hair growth and improve the thickness and density of hair in individuals with hair loss or thinning. - Youthful Appearance
PRP promotes the production of collagen, a protein that helps maintain skin structure and elasticity, leading to a more youthful appearance.
Sexual Health Benefits
- Treats Erectile Dysfunction
PRP therapy has shown promising results in the treatment of erectile dysfunction (ED) by improving blood flow and stimulating tissue regeneration in the penis. - Sexual Satisfaction
PRP injections may enhance sexual satisfaction by improving sensitivity and arousal in both men and women. - Treats Female Sexual Dysfunction
PRP therapy can be used to address various forms of female sexual dysfunction, such as vaginal dryness, decreased libido, and difficulty achieving orgasm.
The platelet-rich plasma is extracted from the patient’s own blood, which means it is really well tolerated with little to no side effects.
What is it?
Platelet-rich plasma (PRP) contains a concentrated mixture of platelets, growth factors, cytokines, and other bioactive proteins that play key roles in the body’s natural healing processes. Here’s a breakdown of some of the components found in PRP and their roles in promoting tissue repair and regeneration:
Platelets
Platelets are small blood cells that are primarily responsible for blood clotting. However, they also contain a variety of growth factors and cytokines that are released when activated. These growth factors play essential roles in tissue repair, including promoting cell proliferation, angiogenesis (formation of new blood vessels), and extracellular matrix synthesis.
Growth Factors
PRP contains several growth factors that are known to stimulate cellular processes involved in tissue regeneration. Some of the key growth factors found in PRP include:
- Platelet-Derived Growth Factor (PDGF)
Stimulates cell proliferation, collagen synthesis, and angiogenesis. - Transforming Growth Factor-beta (TGF-β)
Plays a role in cell differentiation, collagen production, and tissue remodeling. - Vascular Endothelial Growth Factor (VEGF)
Promotes angiogenesis and improves blood flow to the injured area. - Insulin-like Growth Factor (IGF)
Stimulates cell growth and differentiation, contributing to tissue repair and regeneration.
Cytokines
PRP contains various cytokines, which are signaling molecules that regulate immune responses and inflammation. By modulating the inflammatory process, these cytokines help create an optimal environment for tissue healing without excessive inflammation.
Fibrin
Fibrin is a protein involved in the blood clotting process. In PRP therapy, fibrin acts as a scaffold that helps to hold the platelets and other growth factors in place at the site of injury, facilitating tissue repair and regeneration.

For close to 2 years I have suffered from neuropathy in my left leg that resulted in severe pain in my left calf and the loss of about 20% of the strength in my leg. I subsequently met with a top neurosurgeon and after having an MRI was told I would need to have an operation where they would fuse my L4 and L5 discs. I have been being treated by Dr Duncan and his staff for other maintenance issues for the past year and when I shared this news he suggested a treatment. The treatment consisted of PRP Therapy, Exosomes and Peptides mixed together in one injection. In truth I had very little belief that ti would make a difference but who wants a back operation. I am excited and thankful to be able to report that I have been virtually pain free since 10 minutes after the injection. Additionally I am getting my leg back! Strength and stability are returning and the dread of planning an operation that had a 6 month recovery period attached to it is becoming a a non-starter.
I can’t really overstate how dramatic this improvement is any more than I can overstate how good his staff and the service they provide is. Any one reading this that has a similar problem or knows someone suffering or looking into back surgery should do themselves a very large favor and seek the council of Dr, Duncan. I have learned over the past year that he is a wealth of knowledge and at the same time does not “sell” but instead just calmly and with great care gives you options.

What Does a Treatment Look Like?
Some blood is taken from the patient at the beginning of the session. In a centrifuge, the platelet rich plasma is then separated and prepared for injection. This takes about 30-40 minutes to complete. In the last step, this plasma is injected into the body, into or close to the area of concern. A session takes about one hour to complete. Because the plasma is taken from the patient’s own body, this treatment is really well tolerated.
Conclusion
Overall, the combination of platelets, growth factors, cytokines, and fibrin found in PRP works synergistically to promote tissue healing by stimulating cell proliferation, angiogenesis, collagen production, and tissue remodeling. This makes PRP a valuable treatment option for a wide range of orthopedic, aesthetic, and regenerative medicine applications.
It’s important to note that while PRP therapy holds potential benefits in the above mentioned areas, its effectiveness may vary depending on individual factors such as the specific condition being treated, the patient’s overall health, and the expertise of the healthcare provider administering the treatment. Rest assured that Siskiyou Vital Medicine’s physicians are highly trained – Dr. Duncan is one of the teachers of this new modality in our valley. At our clinic, you can get it at a fraction of the cost other clinics charge. More research is needed though to fully understand the long-term effects and optimal applications of PRP therapy in orthopedics, aesthetics, and sexual health.
If you are considering PRP treatment, please consult with Dr. Duncan or your physician to determine if it is a suitable option for your needs.